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Stem Cell Treatment for Spinal Cord Injuries: The newest Frontier<br /><br />[http://www.kneestemcells.com Knee Stem Cells] - Spinal cord injuries are injuries that occur to any level of the spinal cord. Although the hard bones from the spinal column protect the soft tissues of the spinal cord, vertebrae can nonetheless be broken or dislocated in a variety of ways and cause traumatic trouble for the spinal cord. Vertebrae injuries vary inside their severity, but almost inevitably cause various forms of compromised functionality since the spinal cord is in effect the primary pathway for information to travel around the human body. Precisely what body functions are impaired by the injury will depend on the region of the spine which has been damaged and the extent to which the spine may be affected. Although serious impacts including falls and automobile accidents account for many spinal-cord injuries, tumors growing close to the column can also damage sensitive nerve tissue and have the same effects.<br /><br />[http://www.kneestemcells.com Knee Stem Cells] - For decades scientists have been attempting to try and find a way to remedy the different ailments that vertebrae injuries can bring, however with limited success. However, lately a pioneering new technology has emerged that is helping many people around the world regain part, if not completely, of their previously lost mobility. That treatment is the use of stem cells.<br /><br />What exactly are Stem Cells and Stem Cell Treatments?<br /><br />[http://www.kneestemcells.com Knee Stem Cell Injections] - Stem cells are located in all multi cellular organisms and so are characterized by their ability to differentiate into a diverse range of specialized cells once they divide and renew themselves. They are remarkable for their capability to regenerate themselves into any human cell. Their used in the treatment of various diseases and conditions, from Leukemia to Multiple Sclerosis, is now becoming more common. With respect to the condition, stem cells may be transplanted into the patient to assist renew and regenerate previously damaged cells, giving patients renewed hope when, before, no reliable treatment existed.<br /><br />This principle has become being applied to the treatment of spinal cord injuries using stem cells, plus instances where the patient has not yet experienced a complete spinal-cord injury, i.e. a whole severing of the spinal cord leading to a loss of function below the 'neurological' level. There has been positive results in helping patients recover greater sensory and physiological ability.<br /><br />Spinal Cord Injury: How Stem Cell Treatment Works<br /><br />If you find trauma to the spinal cord, myelopathy (damage to the fibres that carry messages to and from the brain) has occurred. These 'myelinated fibre tracts' will be the focus of stem cell treatment, and therefore are the nerve cells how the treatment helps to regenerate. The task usually follows three phases and often requires no longer than the usual period of around five weeks in medical care for monitoring:<br /><br />Phase one requires the harvesting of stem cells. Cells are extracted from a fetus's umbilical cord. They may be then put through an activity whereby they are isolated and purified prior to being finally cultured to become suitable for clinical use.<br /><br />Phase two may be the transplantation of the stem cells. This is accomplished in one of three ways:<br /><br />1) Lumbar puncture - an operation used where stem cells could be injected directly into the backbone.<br /><br />2) Intravenous injection- stem cells are injected to the patient's vein.<br /><br />3) Tissue injection - direct injection into target tissues.<br /><br />Phase three necessitates the monitoring of the patient to make sure there are no adverse side effects. The only side effects reported to date were caused by the lumbar puncture, and never the stem cell treatment itself, just 15% of patients reporting mild headaches. At that time under medical supervision, patients undergo various physiotherapy activities and other treatments as necessary.<br /><br />Stem Cell Research and Treatment in China<br /><br />China is fast becoming a world leader in stem cell research, and is now a major centre for your stem cell treating many diseases and conditions. The Chinese government has poured millions of dollars into research on regenerative medicine, understanding that investment has really borne fruit within the last few years. As a result of this expanded investment, Chinese contributions to scientific journals on regenerative medicine topics leapt from 37 in year 2000 to 1,116 in 2008, exceeded only through the contributions of experts in the united states, Germany, Japan as well as the UK.<br /><br />The government in addition has aggressively recruited high-caliber scientists trained abroad in pursuit of its ambition to become a world leader within the field. Indeed, the McLaughlin-Rotman Centre for Global Health commented that, "the government's policy of attracting highly educated Chinese nationals back to China has contributed significantly to the country's success in the field." The authors were "amazed that almost all the top Chinese researchers inside the regenerative medicine field ended up educated in the US and also the UK and gained extensive experiences there in leading edge research."<br /><br />Although in the past treatment in China might have been considered risky because of lax health and safety laws, recent years have seen an increase in legislation protecting the sufferer, and improving the functionality of clinics. Since 2009, proof of safety and efficacy through clinical trials is required by China's Secretary of state for Health for all stem cell and gene therapies, making sure Chinese clinics meet international standards within their qualifications and methodology. As of January 2010, about 1,500 patients had received botox cosmetic injections for spinal cord injury at one Beijing clinic alone, including roughly 1,000 foreigners.<br /><br />In addition to this, China has long held a location at the forefront of stem cell research to deal with all manner of conditions. A few of China's notable contributions to stem cell research are: <br /><br />By transferring the nucleus of your human skin cell to the immature ovum cell of the rabbit, researchers from your Shanghai hospital successfully produced embryonic human cells.<br />China thus far has created at least 25 human embryonic stem cell lines (some estimate over 70 stem cell lines), four of which are of a specialized type that during those times only two other groups worldwide had managed to create.<br />Harboured several human tissue types, created artificially, including circulation system, tendon, bone, cartilage, skin, cornea and muscle fibre.<br />Furthermore, Chinese researchers are involved with a myriad of projects to help aid patients through regenerative medicine and stem cell therapy. Here are several projects underway within Chinese institutions: <br /><br />ChinaSCINet, a consortium of 27 medical facilities, are beginning phase 2 numerous studies to test the efficacy and safety of using cord blood stem cells and oral lithium to take care of about 40 patients with spinal cord injuries.<br />Clinical trials are underway on the use of stem cell therapies to treat patients of strokes, artery obstruction, and liver and neural diseases.<br />Studies are underway on the potential use of stem cells to deal with heart, liver and blood diseases, eye cataracts, and to combat aging.<br />Testimonials from the Treatment of Spinal Cord Injuries in China<br /><br />Many individuals of all ages and with varying levels of injury have received stem cell treatment in China over the last few years. It is important to understand that not every patient will react as well as others, and that the age of the individual and the severity of the damage greatly affect the likelihood of recovery. However, there were many success stories from both Chinese citizens and foreigners.<br /><br />Before her treatment began in January 2006, Ms. Pai, 38, from Shenyang couldn't move her body below the injury site, and it was unable to control her going number 2. Within 8 months with the treatment she regained movement in both her legs, could bend her knees (even though the toes of one foot remained as paralyzed) and was even capable of walk with crutches.<br /><br />Razvan Iordache, a Romanian citizen aged 30, travelled to China for a number of bouts of stem cell treatment following a major accident while diving right into a river that left him paralyzed in the neck down. Following his treatments, Razan reported in 2008 that not only could he now use his arms almost normally, and could feel pain in many of his fingers, he could "even feel warm and cold" sensations. He proceeded to add the following: "Now I'm able to control my urine for 10 mins and the sensation both for urine and stool is way better. Generally, my entire body is more powerful than before."<br /><br />Donald Maricelli, a 54 year old US citizen, a break down spinal cord injury following a fall in 2002. He underwent an operation to correct his not enough sensation in his lower body, however there was complications and Donald remained in a worse state than ever before. Before arriving for treatment in China, he had been unable to walk unaided. Following the treatment, which commenced in November 2007, Donald makes significant improvements. He regained sensation throughout most of his abdomen, and the sensation in his legs also improved. Particularly important, the sensation on the bottom of his feet returned, helping him simply to walk without tripping. Most important to Donald was he regained control and strength in the left leg, allowing him simply to walk significant distances and stand for prolonged periods of time.<br /><br />There are many more success stories from patients that have received this pioneering treatment to aid correct varying examples of spinal cord injury. However, it will always be important to remember that not all patients recover the identical functions in the same period of time. A lot of hard work goes into the post treatment rehabilitation, plus it takes great drive, determination and ambition to allow the body to get back to more regular functionality. However, the job being done by scientists and clinics in China shows time and again that stem cells hold an essential key to the future of helping people who have spinal cord injuries recover their lost functions. On a monthly basis, more and more people are visiting various cities around the country that offer different packages of treatment based on precisely what injury may be inflicted. The level of service has improved greatly in recent years, and continues to improve each month, meaning that those unfortunate enough to possess suffered spinal cord injuries need no more feel theirs can be a lost cause. There exists a very real chance that the standard of living of any patient may be improved with little pain, little hospital time, along with a little motivation. The present evidence shows that stem cell therapy for spinal-cord injuries is the way forward.