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Stem Cell Strategy for Spinal Cord Injuries: The newest Frontier<br /><br />[http://www.kneestemcells.com Knee Stem Cell Injections] - Spinal cord injuries are injuries that eventually any level of the spinal-cord. Although the hard bones from the spinal column protect the soft tissues of the spinal cord, vertebrae can nonetheless be broken or dislocated in a variety of ways and cause traumatic injury to the spinal cord. Vertebrae injuries vary in their severity, but almost inevitably cause various forms of compromised functionality because the spinal cord is in effect the key pathway for information to visit around the human body. Precisely what body functions are impaired from the injury will depend on the area of the spine that has been damaged and the extent that the spine continues to be affected. Although serious impacts such as falls and car accidents account for many spinal cord injuries, tumors growing near to the column can also damage sensitive nerve tissue and possess the same effects.<br /><br />[http://www.kneestemcells.com Knee Stem Cell Injections] - For years scientists have been attempting to try and find a way to remedy the many ailments that spinal cord injuries can bring, however with limited success. However, recently a pioneering new technology has emerged that is helping many people around the world regain part, if not completely, of their previously lost mobility. That treatment solutions are the use of stem cells.<br /><br />Exactly what are Stem Cells and Stem Cell Treatments?<br /><br />[http://www.kneestemcells.com Knee Stem Cell Injections] - Stem cells are found in all multi cellular organisms and so are characterized by their ability to distinguish into a diverse range of specialized cells once they divide and renew themselves. They are remarkable for their ability to regenerate themselves into almost any other human cell. Their use within the treatment of various diseases and conditions, from Leukemia to Ms, is now becoming more common. Based on the condition, stem cells can be transplanted into the patient to aid renew and regenerate previously damaged cells, giving patients renewed hope when, before, no reliable treatment existed.<br /><br />This principle is currently being applied to the treatment of spinal cord injuries using stem cells, as well as in instances where the patient hasn't experienced a complete vertebrae injury, i.e. a whole severing of the spinal-cord leading to a loss of function underneath the 'neurological' level. There has been positive results in helping patients recover greater sensory and physiological ability.<br /><br />Spinal Cord Injury: How Stem Cell Treatment Works<br /><br />When there is trauma to the vertebrae, myelopathy (damage to the fibres that carry messages both to and from the brain) has occurred. These 'myelinated fibre tracts' are the focus of stem cell treatment, and are the nerve cells that the treatment helps to regenerate. The task usually follows three phases and usually requires no longer when compared to a period of around five weeks in medical treatment for monitoring:<br /><br />Phase one necessitates the harvesting of stem cells. Cellular structure are extracted from a fetus's umbilical cord. They are then put through an activity whereby they are isolated and purified before they are finally cultured being suitable for clinical use.<br /><br />Phase two may be the transplantation of the stem cells. This is accomplished in one of three ways:<br /><br />1) Lumbar puncture - an operation used where stem cells can be injected directly into the spinal column.<br /><br />2) Intravenous injection- stem cells are injected to the patient's vein.<br /><br />3) Tissue injection - direct injection into target tissues.<br /><br />Phase three requires the monitoring of the patient to ensure there are no adverse side effects. The only side effects reported up to now were caused by the lumbar puncture, and not the stem cell treatment itself, with only 15% of patients reporting mild headaches. During the time under medical supervision, patients undergo various physiotherapy activities and other treatments as necessary.<br /><br />Stem Cell Research and Treatment in China<br /><br />China is quickly becoming a world leader in stem cell research, and is now a major centre for the stem cell treatment of many diseases and scenarios. The Chinese government has poured many millions of dollars into research on regenerative medicine, and that investment has really borne fruit in the last few years. As a result of this expanded investment, Chinese contributions to scientific journals on regenerative medicine topics leapt from 37 in year 2000 to 1,116 in 2008, exceeded only by the contributions of experts in the united states, Germany, Japan as well as the UK.<br /><br />The government has additionally aggressively recruited high-caliber scientists trained abroad looking for its ambition to turn into a world leader inside the field. Indeed, the McLaughlin-Rotman Centre for Global Health commented that, "the government's policy of attracting highly educated Chinese nationals to China has contributed significantly to the country's success inside the field." The authors were "amazed that the majority the top Chinese researchers inside the regenerative medicine field have been educated in the US as well as the UK and gained extensive working experience there in cutting edge research."<br /><br />Although in the past treatment in China might have been considered risky because of lax health and safety laws, recent years have seen an increase in legislation protecting the sufferer, and improving the functionality of clinics. Since 2009, proof safety and efficacy through clinical trials is required by China's Secretary of state for Health for all stem cell and gene therapies, making certain Chinese clinics meet international standards within their qualifications and methodology. At the time of January 2010, about 1,500 patients had received this treatment for spinal cord injury at one Beijing clinic alone, including roughly 1,000 foreigners.<br /><br />Additionally, China has long held a spot at the forefront of stem cell research to deal with all manner of conditions. Some of China's notable contributions to stem cell research are: <br /><br />By transferring the nucleus of the human skin cell in to the immature ovum cell of your rabbit, researchers from the Shanghai hospital successfully produced embryonic human cells.<br />China to date has created at least 25 human embryonic stem cell lines (some estimate over 70 stem cell lines), four of which are of a specialized type that during those times only two other groups worldwide had was able to create.<br />Harboured several human tissue types, created artificially, including blood vessel, tendon, bone, cartilage, skin, cornea and muscle fibre.<br />Furthermore, Chinese researchers are involved with a myriad of projects to aid aid patients through regenerative medicine and stem cell therapy. Below are several projects underway within Chinese institutions: <br /><br />ChinaSCINet, a consortium of 27 medical facilities, are beginning phase 2 clinical trials to test the efficacy and safety of employing cord blood stem cells and oral lithium to deal with about 40 patients with spinal cord injuries.<br />Clinical trials are underway about the use of stem cell therapies to treat patients of heart attacks, artery obstruction, and liver and neural diseases.<br />Studies are underway on the potential usage of stem cells to take care of heart, liver and blood diseases, eye cataracts, and also to combat aging.<br />Success Stories from the Treatment of Spinal-cord Injuries in China<br /><br />Many individuals of all ages and with varying degrees of injury have received stem cell treatment in China over the last few years. It is important to understand that not every patient will react and more, and that the age of the patient and the severity of damages greatly affect the chances of recovery. However, there have been many success stories from both Chinese citizens and foreigners.<br /><br />Before her treatment began in January 2006, Ms. Pai, 38, from Shenyang couldn't move her body beneath the injury site, and it was unable to control her bowel motions. Within 8 months of the treatment she regained movement in both her legs, could bend her knees (even though the toes of one foot remained paralyzed) and was even able to walk with crutches.<br /><br />Razvan Iordache, a Romanian citizen aged 30, travelled to China for a number of bouts of stem cell treatment following a major accident while diving into a river that left him paralyzed from your neck down. Following his treatments, Razan reported in 2008 that does not only could he are now using his arms almost normally, and could feel pain in many of his fingers, he could "even feel warm and cold" sensations. He went on to add the following: "Now I'm able to control my urine for Ten minutes and the sensation both for urine and stool is more preferable. Generally, my physique is more powerful than before."<br /><br />Donald Maricelli, a 54 years old US citizen, a break down spinal cord injury following a fall in 2002. He underwent a surgical procedure to correct his insufficient sensation in his lower body, however there have been complications and Donald was left in a worse state than ever before. Before arriving for treatment in China, he was still being unable to walk unaided. Following a treatment, which commenced in November 2007, Donald has created significant improvements. He regained sensation throughout nearly all of his abdomen, and also the sensation in his legs also improved. Particularly crucial, the sensation on the bottom of his feet went back, helping him to walk without tripping. Most critical to Donald was he regained control and strength as part of his left leg, allowing him simply to walk significant distances and are a symbol of prolonged periods of time.<br /><br />There are many more success stories from patients who've received this pioneering treatment to assist correct varying levels of spinal cord injury. However, it will always be important to remember that not all patients recover the identical functions in the same time period. A lot of hard work adopts the post treatment rehabilitation, and it takes great drive, determination and ambition to enable the body to get back to more regular functionality. However, the job being done by scientists and clinics in China has shown time and again that stem cells hold an essential key to the future of helping people with spinal cord injuries recover their lost functions. Each month, more and more people are travelling to various cities across the country that offer different packages of treatment based on precisely what injury continues to be inflicted. The level of service has improved greatly recently, and continues to improve monthly, meaning that those unfortunate enough to possess suffered spinal cord injuries need no more feel theirs can be a lost cause. There's a very real chance how the standard of living of any patient can be improved with little pain, little hospital time, and a little motivation. The present evidence shows that stem cell therapy for spinal-cord injuries is the way forward.