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Stem Cell Strategy to Spinal Cord Injuries: The New Frontier<br /><br />[http://www.kneestemcells.com Knee Stem Cell Injections] - Spinal cord injuries are injuries that eventually any level of the vertebrae. Although the hard bones from the spinal column protect the soft tissues of the spinal cord, vertebrae can still be broken or dislocated in a variety of ways and cause traumatic problems for the spinal cord. Spinal-cord injuries vary within their severity, but almost inevitably result in various forms of compromised functionality as the spinal cord is in effect the main pathway for information to travel around the human body. Precisely what body functions are impaired by the injury will depend on the area of the spine that's been damaged and the extent this agreement the spine may be affected. Although serious impacts including falls and automobile accidents account for many spinal cord injuries, tumors growing close to the column can also damage sensitive nerve tissue and also have the same effects.<br /><br />[http://www.kneestemcells.com Knee Stem Cell Injections] - For many years scientists have been trying to try and find a way to remedy the different ailments that vertebrae injuries can bring, however with limited success. However, recently a pioneering new technologies have emerged that is helping many people around the world regain part, if not completely, of their previously lost mobility. That treatment solutions are the use of stem cells.<br /><br />Exactly what are Stem Cells and Stem Cell Treatments?<br /><br />[http://www.kneestemcells.com Knee Stem Cell Injections] - Stem cells are located in all multi cellular organisms and are characterized by their ability to distinguish into a diverse array of specialized cells after they divide and renew themselves. They may be remarkable for their capability to regenerate themselves into any human cell. Their use within the treatment of various diseases and conditions, from Leukemia to Multiple Sclerosis, is now becoming more common. Depending on the condition, stem cells can be transplanted into the patient to assist renew and regenerate previously damaged cells, giving patients renewed hope when, before, no reliable treatment existed.<br /><br />This principle is currently being applied to treating spinal cord injuries using stem cells, and in instances where the patient has not yet experienced a complete vertebrae injury, i.e. a whole severing of the spinal cord leading to a loss of function beneath the 'neurological' level. There has been positive results in helping patients recover greater sensory and physiological ability.<br /><br />Vertebrae Injury: How Stem Cell Treatment Works<br /><br />When there is trauma to the vertebrae, myelopathy (damage to the fibres that carry messages to and from the brain) has occurred. These 'myelinated fibre tracts' are the focus of stem cell treatment, and therefore are the nerve cells that the treatment helps to regenerate. The process usually follows three phases in most cases requires no longer than a period of around five weeks in health care for monitoring:<br /><br />Phase one involves the harvesting of stem cells. Cellular structure are extracted from a fetus's umbilical cord. They're then put through a process whereby they are isolated and purified prior to being finally cultured to be suitable for clinical use.<br /><br />Phase two may be the transplantation of the stem cells. This is accomplished in one of 3 ways:<br /><br />1) Lumbar puncture - a procedure used where stem cells may be injected directly into the spine.<br /><br />2) Intravenous injection- stem cells are injected to the patient's vein.<br /><br />3) Tissue injection - direct injection into target tissues.<br /><br />Phase three involves the monitoring of the patient to ensure there are no adverse negative effects. The only side effects reported up to now were caused by the lumbar puncture, rather than the stem cell treatment itself, with only 15% of patients reporting mild headaches. At that time under medical supervision, patients undergo various physiotherapy activities along with other treatments as necessary.<br /><br />Stem Cell Research and Treatment in China<br /><br />China is fast-becoming a world leader in stem cell research, and it is now a major centre for that stem cell management of many diseases and conditions. The Chinese government has poured millions of dollars into research on regenerative medicine, which investment has really borne fruit within the last few years. As a result of this expanded investment, Chinese contributions to scientific journals on regenerative medicine topics leapt from 37 in year 2000 to 1,116 in 2008, exceeded only through the contributions of experts in the USA, Germany, Japan as well as the UK.<br /><br />The government has additionally aggressively recruited high-caliber scientists trained abroad in pursuit of its ambition to become a world leader inside the field. Indeed, the McLaughlin-Rotman Centre for Global Health commented that, "the government's policy of attracting highly educated Chinese nationals back to China has contributed significantly to the country's success within the field." The authors were "amazed that almost all the top Chinese researchers within the regenerative medicine field ended up educated in the US and the UK and gained extensive experiences there in innovative research."<br /><br />Although before treatment in China might have been considered risky because of lax health and safety laws, recent years have seen an increase in legislation protecting the sufferer, and improving the functionality of clinics. Since 2009, evidence of safety and efficacy through numerous studies is required by China's Ministry of Health for all stem cell and gene therapies, ensuring that Chinese clinics meet international standards within their qualifications and methodology. As of January 2010, about 1,500 patients had received botox cosmetic injections for spinal cord injury at one Beijing clinic alone, including roughly 1,000 foreigners.<br /><br />Furthermore, China has long held a location at the forefront of stem cell research to treat all manner of conditions. Some of China's notable contributions to stem cell research are: <br /><br />By transferring the nucleus of a human skin cell in to the immature ovum cell of your rabbit, researchers from your Shanghai hospital successfully produced embryonic human cells.<br />China up to now has created at least 25 human embryonic stem cell lines (some estimate over 70 stem cell lines), four of which are of a specialized type that during those times only two other groups worldwide had managed to create.<br />Harboured several human tissue types, created artificially, including circulation system, tendon, bone, cartilage, skin, cornea and muscle fibre.<br />Furthermore, Chinese researchers are currently involved with a myriad of projects to aid aid patients through regenerative medicine and stem cell therapy. Here are several projects underway within Chinese institutions: <br /><br />ChinaSCINet, a consortium of 27 medical facilities, are beginning phase 2 clinical trials to test the efficacy and safety of employing cord blood stem cells and oral lithium to treat about 40 patients with spinal-cord injuries.<br />Clinical trials are underway about the use of stem cell therapies to deal with patients of cardiac arrest, artery obstruction, and liver and neural diseases.<br />Research is underway on the potential utilization of stem cells to deal with heart, liver and blood diseases, eye cataracts, also to combat aging.<br />Testimonials from the Treatment of Vertebrae Injuries in China<br /><br />Lots of people of all ages and with varying levels of injury have received stem cell treatment in China over the last few years. It is important to understand that not every patient will react and more, and that the age of the sufferer and the severity of damages greatly affect the chances of recovery. However, there have been many success stories from both Chinese citizens and foreigners.<br /><br />Before her treatment began in January 2006, Ms. Pai, 38, from Shenyang couldn't move her body below the injury site, and it was unable to control her bowel movements. Within 8 months from the treatment she regained movement in the her legs, could bend her knees (although the toes of one foot remained as paralyzed) and was even in a position to walk with crutches.<br /><br />Razvan Iordache, a Romanian citizen aged 30, travelled to China for many bouts of stem cell treatment following a major accident while diving into a river that left him paralyzed in the neck down. Following his treatments, Razan reported in 2008 that doesn't only could he are now using his arms almost normally, and might feel pain in a number of of his fingers, he could "even feel warm and cold" sensations. He proceeded to add the following: "Now I will control my urine for Ten minutes and the sensation for urine and stool is more preferable. Generally, my entire body is more powerful than ever before."<br /><br />Donald Maricelli, a 54 year old US citizen, a break down spinal cord injury using a fall in 2002. He underwent an operation to correct his lack of sensation in his lower body, however there have been complications and Donald stayed in a worse state than before. Before arriving for treatment in China, he had been unable to walk unaided. Following a treatment, which commenced in November 2007, Donald has made significant improvements. He regained sensation throughout nearly all of his abdomen, as well as the sensation in his legs also improved. Particularly significant, the sensation on the bottom of his feet came back, helping him simply to walk without tripping. Most significant to Donald was he regained control and strength as part of his left leg, allowing him to walk significant distances and stand for prolonged periods of time.<br /><br />There are lots of more success stories from patients who have received this pioneering treatment to assist correct varying degrees of spinal cord injury. However, it is always important to remember that not all patients recover exactly the same functions in the same time frame. A lot of hard work switches into the post treatment rehabilitation, plus it takes great drive, determination and ambition to allow the body to get back to more regular functionality. However, the job being done by scientists and clinics in China has shown time and again that stem cells hold an essential key to the future of helping people who have spinal cord injuries recover their lost functions. On a monthly basis, more and more people are visiting various cities around the country that offer different packages of treatment based on precisely what injury has been inflicted. The level of service has improved greatly lately, and continues to improve monthly, meaning that those unfortunate enough to have suffered spinal cord injuries need will no longer feel theirs can be a lost cause. There exists a very real chance that the standard of living of any patient may be improved with little pain, little hospital time, along with a little motivation. The current evidence shows that stem cell therapy for spinal cord injuries is the way forward.