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Stem Cell Strategy for Spinal Cord Injuries: The New Frontier<br /><br />[http://www.kneestemcells.com Knee Stem Cell Injections] - Spinal cord injuries are injuries that eventually any level of the vertebrae. Although the hard bones with the spinal column protect the soft tissues with the spinal cord, vertebrae can nonetheless be broken or dislocated in many different ways and cause traumatic problems for the spinal cord. Spinal-cord injuries vary within their severity, but almost inevitably result in various forms of compromised functionality since the spinal cord is in effect the key pathway for information to visit around the human body. Precisely what body functions are impaired from the injury will depend on the location of the spine which has been damaged and the extent to which the spine has been affected. Although serious impacts including falls and motor vehicle accidents account for many spinal cord injuries, tumors growing near to the column can also damage sensitive nerve tissue and also have the same effects.<br /><br />[http://www.kneestemcells.com Knee Stem Cell Injections] - For years scientists have been attempting to try and find a way to remedy the many ailments that spinal cord injuries can bring, though limited success. However, recently a pioneering new technologies have emerged that is helping many people around the world regain part, if not all, of their previously lost mobility. That treatment is the use of stem cells.<br /><br />What are Stem Cells and Stem Cell Treatments?<br /><br />[http://www.kneestemcells.com Knee Stem Cell Treatment] - Stem cells are located in all multi cellular organisms and so are characterized by their ability to differentiate into a diverse array of specialized cells once they divide and renew themselves. They are remarkable for their capability to regenerate themselves into just about any human cell. Their used in the treatment of various diseases and conditions, from Leukemia to Multiple Sclerosis, is now becoming more common. Based on the condition, stem cells could be transplanted into the patient to assist renew and regenerate previously damaged cells, giving patients renewed hope when, before, no reliable treatment existed.<br /><br />This principle has become being applied to the management of spinal cord injuries using stem cells, as well as in instances where the patient has not experienced a complete spinal-cord injury, i.e. a complete severing of the spinal-cord leading to a loss of function underneath the 'neurological' level. There has been positive results in helping patients recover greater sensory and physiological ability.<br /><br />Vertebrae Injury: How Stem Cell Treatment Works<br /><br />If you have trauma to the spinal cord, myelopathy (damage to the fibres that carry messages both to and from the brain) has occurred. These 'myelinated fibre tracts' will be the focus of stem cell treatment, and are the nerve cells that the treatment helps to regenerate. The procedure usually follows three phases and usually requires no longer when compared to a period of around five weeks in medical care for monitoring:<br /><br />Phase one requires the harvesting of stem cells. Cells are extracted from a fetus's umbilical cord. They are then put through a process whereby they are isolated and purified prior to being finally cultured being suitable for clinical use.<br /><br />Phase two will be the transplantation of the stem cells. This is done in one of three ways:<br /><br />1) Lumbar puncture - an operation used where stem cells could be injected directly into the spinal column.<br /><br />2) Intravenous injection- stem cells are injected in to the patient's vein.<br /><br />3) Tissue injection - direct injection into target tissues.<br /><br />Phase three requires the monitoring of the patient to make certain there are no adverse unwanted effects. The only side effects reported up to now were caused by the lumbar puncture, and not the stem cell treatment itself, with simply 15% of patients reporting mild headaches. At that time under medical supervision, patients undergo various physiotherapy activities along with other treatments as necessary.<br /><br />Stem Cell Research and Treatment in China<br /><br />China is fast-becoming a world leader in stem cell research, and it is now a major centre for the stem cell treating many diseases and conditions. The Chinese government has poured millions of dollars into research on regenerative medicine, which investment has really borne fruit within the last few years. As a result of this expanded investment, Chinese contributions to scientific journals on regenerative medicine topics leapt from 37 in 2000 to 1,116 in 2008, exceeded only from the contributions of experts in the USA, Germany, Japan as well as the UK.<br /><br />The government has additionally aggressively recruited high-caliber scientists trained abroad looking for its ambition to become a world leader within the field. Indeed, the McLaughlin-Rotman Centre for Global Health commented that, "the government's policy of attracting highly educated Chinese nationals to China has contributed significantly towards the country's success within the field." The authors were "amazed that almost all the top Chinese researchers in the regenerative medicine field had been educated in the US and also the UK and gained extensive working experience there in innovative research."<br /><br />Although before treatment in China may have been considered risky due to lax health and safety laws, recent years have seen an increase in legislation protecting the sufferer, and improving the functionality of clinics. Since 2009, proof of safety and efficacy through numerous studies is required by China's Ministry of Health for all stem cell and gene therapies, making certain Chinese clinics meet international standards inside their qualifications and methodology. At the time of January 2010, about 1,500 patients had received botox cosmetic injections for spinal cord injury at one Beijing clinic alone, including roughly 1,000 foreigners.<br /><br />In addition to this, China has long held a spot at the forefront of stem cell research to deal with all manner of conditions. Some of China's notable contributions to stem cell research are: <br /><br />By transferring the nucleus of the human skin cell in to the immature ovum cell of your rabbit, researchers from the Shanghai hospital successfully produced embryonic human cells.<br />China to date has created at least 25 human embryonic stem cell lines (some estimate over 70 stem cell lines), four that are of a specialized type that in those days only two other groups worldwide had were able to create.<br />Harboured several human tissue types, created artificially, including circulation system, tendon, bone, cartilage, skin, cornea and muscle fibre.<br />Furthermore, Chinese researchers are involved with a myriad of projects to aid aid patients through regenerative medicine and stem cell therapy. Below are several projects underway within Chinese institutions: <br /><br />ChinaSCINet, a consortium of 27 medical facilities, are beginning phase 2 numerous studies to test the efficacy and safety of employing cord blood stem cells and oral lithium to take care of about 40 patients with vertebrae injuries.<br />Clinical trials are underway on the use of stem cell therapies to treat patients of heart attacks, artery obstruction, and liver and neural diseases.<br />Studies are underway on the potential utilization of stem cells to take care of heart, liver and blood diseases, eye cataracts, also to combat aging.<br />Testimonials from the Treatment of Vertebrae Injuries in China<br /><br />Many people of all ages and with varying degrees of injury have received stem cell treatment in China over the last few years. It is important to keep in mind that not every patient will react as well as others, and that the age of the individual and the severity of the injury greatly affect the odds of recovery. However, there were many success stories from both Chinese citizens and foreigners.<br /><br />Before her treatment began in January 2006, Ms. Pai, 38, from Shenyang couldn't move her body underneath the injury site, and it was unable to control her bowel motions. Within 8 months from the treatment she regained movement in both her legs, could bend her knees (even though toes of one foot remained paralyzed) and was even in a position to walk with crutches.<br /><br />Razvan Iordache, a Romanian citizen aged 30, travelled to China for a number of bouts of stem cell treatment following any sort of accident while diving right into a river that left him paralyzed in the neck down. Following his treatments, Razan reported in 2008 that not only could he moved to his arms almost normally, and could feel pain in several of his fingers, he could "even feel warm and cold" sensations. He went on to add the following: "Now I will control my urine for 10 minutes and the sensation both for urine and stool is much better. Generally, my physique is more powerful than ever before."<br /><br />Donald Maricelli, a 54 year old US citizen, a break down spinal cord injury carrying out a fall in 2002. He underwent an operation to correct his lack of sensation in his lower body, however there was complications and Donald stayed in a worse state than before. Before arriving for treatment in China, he had been unable to walk unaided. Following a treatment, which commenced in November 2007, Donald has created significant improvements. He regained sensation throughout most of his abdomen, as well as the sensation in his legs also improved. Particularly significant, the sensation on the bottom of his feet returned, helping him to walk without tripping. Most significant to Donald was he regained control and strength as part of his left leg, allowing him to walk significant distances and are a symbol of prolonged periods of time.<br /><br />There are numerous more success stories from patients who have received this pioneering treatment to help correct varying degrees of spinal cord injury. However, it is always important to remember that not all patients recover exactly the same functions in the same period of time. A lot of hard work switches into the post treatment rehabilitation, and it takes great drive, determination and ambition make it possible for the body to get back to more regular functionality. However, the job being done by scientists and clinics in China shows time and again that stem cells hold a critical key to the future of helping individuals with spinal cord injuries recover their lost functions. On a monthly basis, more and more people are going to various cities round the country that offer different packages of treatment based on precisely what injury may be inflicted. The level of service has improved greatly in recent years, and continues to improve each month, meaning that those unfortunate enough to get suffered spinal cord injuries need will no longer feel theirs is a lost cause. There exists a very real chance that the standard of living of any patient could be improved with little pain, little hospital time, along with a little motivation. The present evidence shows that stem cell therapy for vertebrae injuries is the way forward.