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Stem Cell Strategy for Spinal Cord Injuries: The New Frontier<br /><br />[http://www.kneestemcells.com Knee Stem Cells] - Spinal cord injuries are injuries that happen to any level of the spinal cord. Although the hard bones from the spinal column protect the soft tissues of the spinal cord, vertebrae can nonetheless be broken or dislocated in a number of ways and cause traumatic trouble for the spinal cord. Spinal cord injuries vary inside their severity, but almost inevitably result in various forms of compromised functionality since the spinal cord is in effect the primary pathway for information to visit around the human body. Precisely what body functions are impaired from the injury will depend on the area of the spine that's been damaged and the extent that the spine may be affected. Although serious impacts including falls and automobile accidents account for many spinal cord injuries, tumors growing close to the column can also damage sensitive nerve tissue and also have the same effects.<br /><br />[http://www.kneestemcells.com Knee Stem Cell Injections] - For decades scientists have been working to try and find a way to remedy the many ailments that spinal cord injuries can bring, though limited success. However, recently a pioneering new technologies have emerged that is helping thousands of people around the world regain part, if not completely, of their previously lost mobility. That treatment solutions are the use of stem cells.<br /><br />Exactly what are Stem Cells and Stem Cell Treatments?<br /><br />[http://www.kneestemcells.com Knee Stem Cell Treatment] - Stem cells are located in all multi cellular organisms and are characterized by their ability to distinguish into a diverse selection of specialized cells when they divide and renew themselves. They may be remarkable for their ability to regenerate themselves into just about any human cell. Their use within the treatment of various diseases and conditions, from Leukemia to Ms, is now becoming more common. Based on the condition, stem cells can be transplanted into the patient to help renew and regenerate previously damaged cells, giving patients renewed hope when, before, no reliable treatment existed.<br /><br />This principle is currently being applied to the management of spinal cord injuries using stem cells, and in instances where the patient hasn't experienced a complete spinal-cord injury, i.e. a whole severing of the spinal cord leading to a loss of function underneath the 'neurological' level. There has been great success in helping patients recover greater sensory and physiological ability.<br /><br />Spinal-cord Injury: How Stem Cell Treatment Works<br /><br />If you have trauma to the vertebrae, myelopathy (damage to the fibres that carry messages to and from the brain) has occurred. These 'myelinated fibre tracts' are the focus of stem cell treatment, and are the nerve cells the treatment helps to regenerate. The procedure usually follows three phases in most cases requires no longer than a period of around five weeks in medical care for monitoring:<br /><br />Phase one involves the harvesting of stem cells. Cells are extracted from a fetus's umbilical cord. They're then put through a procedure whereby they are isolated and purified before they are finally cultured to be suitable for clinical use.<br /><br />Phase two is the transplantation of the stem cells. This is done in one of three ways:<br /><br />1) Lumbar puncture - an operation used where stem cells could be injected directly into the backbone.<br /><br />2) Intravenous injection- stem cells are injected into the patient's vein.<br /><br />3) Tissue injection - direct injection into target tissues.<br /><br />Phase three necessitates the monitoring of the patient to make certain there are no adverse side effects. The only side effects reported thus far were caused by the lumbar puncture, rather than the stem cell treatment itself, with only 15% of patients reporting mild headaches. At that time under medical supervision, patients undergo various physiotherapy activities as well as other treatments as necessary.<br /><br />Stem Cell Research and Treatment in China<br /><br />China is fast-becoming a world leader in stem cell research, and is also now a major centre for your stem cell management of many diseases and conditions. The Chinese government has poured millions of dollars into research on regenerative medicine, and that investment has really borne fruit in the last few years. As a result of this expanded investment, Chinese contributions to scientific journals on regenerative medicine topics leapt from 37 in 2000 to 1,116 in 2008, exceeded only by the contributions of experts in the USA, Germany, Japan as well as the UK.<br /><br />The government in addition has aggressively recruited high-caliber scientists trained abroad looking for its ambition to become a world leader within the field. Indeed, the McLaughlin-Rotman Centre for Global Health commented that, "the government's policy of attracting highly educated Chinese nationals returning to China has contributed significantly to the country's success within the field." The authors were "amazed that the majority the top Chinese researchers in the regenerative medicine field have been educated in the US and also the UK and gained extensive working experience there in cutting edge research."<br /><br />Although previously treatment in China may have been considered risky due to lax health and safety laws, recent years have seen an increase in legislation protecting the individual, and improving the functionality of clinics. Since 2009, evidence of safety and efficacy through clinical trials is required by China's Ministry of Health for all stem cell and gene therapies, making certain Chinese clinics meet international standards in their qualifications and methodology. At the time of January 2010, about 1,500 patients had received laser hair removal for spinal cord injury at one Beijing clinic alone, including roughly 1,000 foreigners.<br /><br />Additionally, China has long held a place at the forefront of stem cell research to treat all manner of conditions. Some of China's notable contributions to stem cell research are: <br /><br />By transferring the nucleus of your human skin cell into the immature ovum cell of your rabbit, researchers from a Shanghai hospital successfully produced embryonic human cells.<br />China thus far has created at least 25 human embryonic stem cell lines (some estimate over 70 stem cell lines), four which are of a specialized type that during those times only two other groups worldwide had were able to create.<br />Harboured several human tissue types, created artificially, including circulation system, tendon, bone, cartilage, skin, cornea and muscle fibre.<br />Furthermore, Chinese researchers are currently involved with a myriad of projects to assist aid patients through regenerative medicine and stem cell therapy. Listed here are several projects underway within Chinese institutions: <br /><br />ChinaSCINet, a consortium of 27 medical facilities, are starting phase 2 many studies to test the efficacy and safety of utilizing cord blood stem cells and oral lithium to deal with about 40 patients with vertebrae injuries.<br />Clinical trials are underway around the use of stem cell therapies to deal with patients of cardiac arrest, artery obstruction, and liver and neural diseases.<br />Research is underway on the potential use of stem cells to deal with heart, liver and blood diseases, eye cataracts, and also to combat aging.<br />Success Stories from the Treatment of Vertebrae Injuries in China<br /><br />Lots of people of all ages and with varying levels of injury have received stem cell treatment in China during the last few years. It is important to remember that not every patient will react and more, and that the age of the patient and the severity of the injury greatly affect the likelihood of recovery. However, there have been many success stories from both Chinese citizens and foreigners.<br /><br />Before her treatment began in January 2006, Ms. Pai, 38, from Shenyang couldn't move her body below the injury site, and was unable to control her going number 2. Within 8 months of the treatment she regained movement in both her legs, could bend her knees (even though toes of one foot remained paralyzed) and was even in a position to walk with crutches.<br /><br />Razvan Iordache, a Romanian citizen aged 30, travelled to China for several bouts of stem cell treatment following an accident while diving into a river that left him paralyzed from your neck down. Following his treatments, Razan reported in 2008 that does not only could he are now using his arms almost normally, and may feel pain in a number of of his fingers, he could "even feel warm and cold" sensations. He went on to add the following: "Now I'm able to control my urine for 10 mins and the sensation for both urine and stool is way better. Generally, my system is more powerful than before."<br /><br />Donald Maricelli, a 54 year old US citizen, suffered a spinal cord injury following a fall in 2002. He underwent surgery to correct his not enough sensation in his lower body, however there have been complications and Donald was left in a worse state than before. Before arriving for treatment in China, he had been unable to walk unaided. Pursuing the treatment, which commenced in November 2007, Donald makes significant improvements. He regained sensation throughout most of his abdomen, as well as the sensation in his legs also improved. Particularly crucial, the sensation on the bottom of his feet returned, helping him just to walk without tripping. Most critical to Donald was which he regained control and strength as part of his left leg, allowing him just to walk significant distances and are a symbol of prolonged periods of time.<br /><br />There are numerous more success stories from patients that have received this pioneering treatment to aid correct varying degrees of spinal cord injury. However, it is always important to remember that not all patients recover exactly the same functions in the same time frame. A lot of hard work adopts the post treatment rehabilitation, and it takes great drive, determination and ambition to enable the body to get back to more regular functionality. However, the task being done by scientists and clinics in China shows time and again that stem cells hold a very important key to the future of helping people who have spinal cord injuries recover their lost functions. On a monthly basis, more and more people are travelling to various cities across the country that offer different packages of treatment according to precisely what injury may be inflicted. The level of service has improved greatly in recent years, and continues to improve monthly, meaning that those unfortunate enough to possess suffered spinal cord injuries need no longer feel theirs can be a lost cause. There is a very real chance the standard of living of any patient could be improved with little pain, little hospital time, plus a little motivation. The current evidence shows that stem cell therapy for spinal cord injuries is the answer.