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Stem Cell Strategy for Spinal Cord Injuries: The brand new Frontier<br /><br />[http://www.kneestemcells.com Knee Stem Cells] - Spinal cord injuries are injuries that happen to any level of the spinal-cord. Although the hard bones of the spinal column protect the soft tissues with the spinal cord, vertebrae can nevertheless be broken or dislocated in a variety of ways and cause traumatic injury to the spinal cord. Spinal-cord injuries vary in their severity, but almost inevitably result in various forms of compromised functionality as the spinal cord is in effect the key pathway for information to travel around the human body. Just what body functions are impaired through the injury will depend on the area of the spine which has been damaged and the extent to which the spine continues to be affected. Although serious impacts for example falls and motor vehicle accidents account for many spinal cord injuries, tumors growing close to the column can also damage sensitive nerve tissue and also have the same effects.<br /><br />[http://www.kneestemcells.com Knee Stem Cell Treatment] - For many years scientists have been attempting to try and find a way to remedy the many ailments that spinal cord injuries can bring, however with limited success. However, lately a pioneering new technology has emerged that is helping lots of people around the world regain part, it not exclusively, of their previously lost mobility. That treatment solutions are the use of stem cells.<br /><br />What are Stem Cells and Stem Cell Treatments?<br /><br />[http://www.kneestemcells.com Knee Stem Cell Treatment] - Stem cells are located in all multi cellular organisms and so are characterized by their ability to differentiate into a diverse selection of specialized cells after they divide and renew themselves. They may be remarkable for their capability to regenerate themselves into any human cell. Their use in the treatment of various diseases and types of conditions, from Leukemia to Ms, is now becoming more common. Depending on the condition, stem cells may be transplanted into the patient to help renew and regenerate previously damaged cells, giving patients renewed hope when, before, no reliable treatment existed.<br /><br />This principle has become being applied to the treatment of spinal cord injuries using stem cells, and in instances where the patient has not yet experienced a complete spinal-cord injury, i.e. a complete severing of the spinal-cord leading to a loss of function beneath the 'neurological' level. There has been positive results in helping patients recover greater sensory and physiological ability.<br /><br />Spinal Cord Injury: How Stem Cell Treatment Works<br /><br />When there is trauma to the spinal cord, myelopathy (damage to the fibres that carry messages both to and from the brain) has occurred. These 'myelinated fibre tracts' will be the focus of stem cell treatment, and so are the nerve cells that the treatment helps to regenerate. The procedure usually follows three phases and often requires no longer than the usual period of around five weeks in health care for monitoring:<br /><br />Phase one involves the harvesting of stem cells. The cells are extracted from a fetus's umbilical cord. They're then put through an activity whereby they are isolated and purified prior to being finally cultured to become suitable for clinical use.<br /><br />Phase two will be the transplantation of the stem cells. This is achieved in one of 3 ways:<br /><br />1) Lumbar puncture - a process used where stem cells can be injected directly into the backbone.<br /><br />2) Intravenous injection- stem cells are injected in to the patient's vein.<br /><br />3) Tissue injection - direct injection into target tissues.<br /><br />Phase three involves the monitoring of the patient to ensure there are no adverse side effects. The only side effects reported up to now were caused by the lumbar puncture, rather than the stem cell treatment itself, with simply 15% of patients reporting mild headaches. During the time under medical supervision, patients undergo various physiotherapy activities and other treatments as necessary.<br /><br />Stem Cell Research and Treatment in China<br /><br />China is fast-becoming a world leader in stem cell research, and it is now a major centre for the stem cell treatment of many diseases and scenarios. The Chinese government has poured millions of dollars into research on regenerative medicine, which investment has really borne fruit in the last few years. As a result of this expanded investment, Chinese contributions to scientific journals on regenerative medicine topics leapt from 37 in year 2000 to 1,116 in 2008, exceeded only from the contributions of experts in the USA, Germany, Japan as well as the UK.<br /><br />The government has also aggressively recruited high-caliber scientists trained abroad in pursuit of its ambition to become world leader within the field. Indeed, the McLaughlin-Rotman Centre for Global Health commented that, "the government's policy of attracting highly educated Chinese nationals back to China has contributed significantly to the country's success inside the field." The authors were "amazed that almost all the top Chinese researchers inside the regenerative medicine field had been educated in the US as well as the UK and gained extensive experiences there in leading edge research."<br /><br />Although before treatment in China could have been considered risky because of lax health and safety laws, the past few years have seen an increase in legislation protecting the sufferer, and improving the functionality of clinics. Since 2009, evidence of safety and efficacy through numerous studies is required by China's Ministry of Health for all stem cell and gene therapies, ensuring that Chinese clinics meet international standards in their qualifications and methodology. By January 2010, about 1,500 patients had received this treatment for spinal cord injury at one Beijing clinic alone, including roughly 1,000 foreigners.<br /><br />Furthermore, China has long held a place at the forefront of stem cell research to deal with all manner of conditions. Some of China's notable contributions to stem cell research are: <br /><br />By transferring the nucleus of the human skin cell in to the immature ovum cell of your rabbit, researchers from a Shanghai hospital successfully produced embryonic human cells.<br />China to date has created at least 25 human embryonic stem cell lines (some estimate over 70 stem cell lines), four which are of a specialized type that during those times only two other groups worldwide had managed to create.<br />Harboured several human tissue types, created artificially, including circulation system, tendon, bone, cartilage, skin, cornea and muscle fibre.<br />Furthermore, Chinese researchers are presently involved with a myriad of projects to assist aid patients through regenerative medicine and stem cell therapy. Here are several projects underway within Chinese institutions: <br /><br />ChinaSCINet, a consortium of 27 medical facilities, start phase 2 numerous studies to test the efficacy and safety of employing cord blood stem cells and oral lithium to deal with about 40 patients with spinal cord injuries.<br />Clinical trials are underway around the use of stem cell therapies to take care of patients of heart attacks, artery obstruction, and liver and neural diseases.<br />Studies are underway on the potential utilization of stem cells to deal with heart, liver and blood diseases, eye cataracts, and also to combat aging.<br />Testimonials from the Treatment of Spinal-cord Injuries in China<br /><br />Many individuals of all ages and with varying levels of injury have received stem cell treatment in China throughout the last few years. It is important to keep in mind that not every patient will react as well as others, and that the age of the patient and the severity of the injury greatly affect the odds of recovery. However, there have been many success stories from both Chinese citizens and foreigners.<br /><br />Before her treatment began in January 2006, Ms. Pai, 38, from Shenyang couldn't move her body underneath the injury site, and was unable to control her going number 2. Within 8 months from the treatment she regained movement in both her legs, could bend her knees (even though toes of one foot were still paralyzed) and was even capable of walk with crutches.<br /><br />Razvan Iordache, a Romanian citizen aged 30, travelled to China for many bouts of stem cell treatment following a major accident while diving in to a river that left him paralyzed in the neck down. Following his treatments, Razan reported in 2008 that doesn't only could he are now using his arms almost normally, and might feel pain in several of his fingers, he could "even feel warm and cold" sensations. He proceeded to add the following: "Now I'm able to control my urine for Ten minutes and the sensation for both urine and stool is more preferable. Generally, my entire body is more powerful than before."<br /><br />Donald Maricelli, a 54 years old US citizen, a break down spinal cord injury carrying out a fall in 2002. He underwent an operation to correct his lack of sensation in his lower body, however there were complications and Donald stayed in a worse state than before. Before arriving for treatment in China, he was still unable to walk unaided. Following the treatment, which commenced in November 2007, Donald has made significant improvements. He regained sensation throughout most of his abdomen, and also the sensation in his legs also improved. Particularly significant, the sensation on the bottom of his feet came back, helping him just to walk without tripping. Most significant to Donald was which he regained control and strength as part of his left leg, allowing him to walk significant distances and are a symbol of prolonged periods of time.<br /><br />There are lots of more success stories from patients who have received this pioneering treatment to aid correct varying degrees of spinal cord injury. However, it will always be important to remember that not all patients recover the same functions in the same time period. A lot of hard work switches into the post treatment rehabilitation, plus it takes great drive, determination and ambition make it possible for the body to get back to more regular functionality. However, the job being done by scientists and clinics in China indicates time and again that stem cells hold an essential key to the future of helping people with spinal cord injuries recover their lost functions. Every month, more and more people are visiting various cities round the country that offer different packages of treatment depending on precisely what injury continues to be inflicted. The level of service has improved greatly recently, and continues to improve each month, meaning that those unfortunate enough to possess suffered spinal cord injuries need no more feel theirs can be a lost cause. There's a very real chance the standard of living of any patient may be improved with little pain, little hospital time, plus a little motivation. The current evidence shows that stem cell therapy for vertebrae injuries is the way forward.