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Stem Cell Treatment for Spinal Cord Injuries: The New Frontier<br /><br />[http://www.kneestemcells.com Knee Stem Cells] - Spinal cord injuries are injuries that happen to any level of the spinal cord. Although the hard bones of the spinal column protect the soft tissues with the spinal cord, vertebrae can nonetheless be broken or dislocated in a number of ways and cause traumatic problems for the spinal cord. Spinal-cord injuries vary in their severity, but almost inevitably lead to various forms of compromised functionality since the spinal cord is in effect the key pathway for information traveling around the human body. Precisely what body functions are impaired through the injury will depend on the region of the spine that has been damaged and the extent to which the spine has been affected. Although serious impacts including falls and car accidents account for many spinal cord injuries, tumors growing near the column can also damage sensitive nerve tissue and also have the same effects.<br /><br />[http://www.kneestemcells.com Knee Stem Cell Injections] - For many years scientists have been attempting to try and find a way to remedy the various ailments that spinal-cord injuries can bring, however with limited success. However, in recent years a pioneering new technologies have emerged that is helping many people around the world regain part, it not exclusively, of their previously lost mobility. That treatment is the use of stem cells.<br /><br />Exactly what are Stem Cells and Stem Cell Treatments?<br /><br />[http://www.kneestemcells.com Knee Stem Cell Treatment] - Stem cells are simply in all multi cellular organisms and therefore are characterized by their ability to tell apart into a diverse array of specialized cells after they divide and renew themselves. They are remarkable for their capability to regenerate themselves into almost any other human cell. Their used in the treatment of various diseases and scenarios, from Leukemia to Multiple Sclerosis, is now becoming more common. Depending on the condition, stem cells can be transplanted into the patient to assist renew and regenerate previously damaged cells, giving patients renewed hope when, before, no reliable treatment existed.<br /><br />This principle has become being applied to the management of spinal cord injuries using stem cells, and in instances where the patient has not experienced a complete spinal-cord injury, i.e. an entire severing of the spinal-cord leading to a loss of function underneath the 'neurological' level. There has been great success in helping patients recover greater sensory and physiological ability.<br /><br />Vertebrae Injury: How Stem Cell Treatment Works<br /><br />When there is trauma to the spinal cord, myelopathy (damage to the fibres that carry messages both to and from the brain) has occurred. These 'myelinated fibre tracts' will be the focus of stem cell treatment, and so are the nerve cells how the treatment helps to regenerate. The task usually follows three phases and usually requires no longer when compared to a period of around five weeks in medical treatment for monitoring:<br /><br />Phase one involves the harvesting of stem cells. Cells are extracted from a fetus's umbilical cord. They're then put through a process whereby they are isolated and purified prior to being finally cultured to be suitable for clinical use.<br /><br />Phase two is the transplantation of the stem cells. This is done in one of 3 ways:<br /><br />1) Lumbar puncture - an operation used where stem cells could be injected directly into the spinal column.<br /><br />2) Intravenous injection- stem cells are injected into the patient's vein.<br /><br />3) Tissue injection - direct injection into target tissues.<br /><br />Phase three necessitates the monitoring of the patient to make certain there are no adverse side effects. The only side effects reported up to now were caused by the lumbar puncture, rather than the stem cell treatment itself, just 15% of patients reporting mild headaches. During the time under medical supervision, patients undergo various physiotherapy activities and other treatments as necessary.<br /><br />Stem Cell Research and Treatment in China<br /><br />China is quickly becoming a world leader in stem cell research, and it is now a major centre for your stem cell management of many diseases and types of conditions. The Chinese government has poured many millions of dollars into research on regenerative medicine, understanding that investment has really borne fruit within the last few years. As a result of this expanded investment, Chinese contributions to scientific journals on regenerative medicine topics leapt from 37 in 2000 to 1,116 in 2008, exceeded only from the contributions of experts in the USA, Germany, Japan and the UK.<br /><br />The government has additionally aggressively recruited high-caliber scientists trained abroad in pursuit of its ambition to turn into a world leader within the field. Indeed, the McLaughlin-Rotman Centre for Global Health commented that, "the government's policy of attracting highly educated Chinese nationals back to China has contributed significantly to the country's success in the field." The authors were "amazed that almost all the top Chinese researchers in the regenerative medicine field ended up educated in the US and the UK and gained extensive practical knowledge there in cutting edge research."<br /><br />Although before treatment in China could have been considered risky due to lax health and safety laws, recent times have seen an increase in legislation protecting the individual, and improving the functionality of clinics. Since 2009, proof safety and efficacy through clinical trials is required by China's Secretary of state for Health for all stem cell and gene therapies, making certain Chinese clinics meet international standards inside their qualifications and methodology. As of January 2010, about 1,500 patients had received laser hair removal for spinal cord injury at one Beijing clinic alone, including roughly 1,000 foreigners.<br /><br />Additionally, China has long held a place at the forefront of stem cell research to take care of all manner of conditions. A number of China's notable contributions to stem cell research are: <br /><br />By transferring the nucleus of your human skin cell to the immature ovum cell of a rabbit, researchers from a Shanghai hospital successfully produced embryonic human cells.<br />China to date has created at least 25 human embryonic stem cell lines (some estimate over 70 stem cell lines), four that are of a specialized type that during those times only two other groups worldwide had was able to create.<br />Harboured several human tissue types, created artificially, including circulation system, tendon, bone, cartilage, skin, cornea and muscle fibre.<br />Furthermore, Chinese researchers are presently involved with a myriad of projects to aid aid patients through regenerative medicine and stem cell therapy. Here are several projects underway within Chinese institutions: <br /><br />ChinaSCINet, a consortium of 27 medical facilities, are starting phase 2 many studies to test the efficacy and safety of employing cord blood stem cells and oral lithium to treat about 40 patients with spinal-cord injuries.<br />Clinical trials are underway around the use of stem cell therapies to treat patients of heart attacks, artery obstruction, and liver and neural diseases.<br />Research is underway on the potential utilization of stem cells to treat heart, liver and blood diseases, eye cataracts, also to combat aging.<br />Success Stories from the Treatment of Spinal-cord Injuries in China<br /><br />Many individuals of all ages and with varying examples of injury have received stem cell treatment in China throughout the last few years. It is important to understand that not every patient will react as well as others, and that the age of the patient and the severity of the injury greatly affect the odds of recovery. However, there has been many success stories from both Chinese citizens and foreigners.<br /><br />Before her treatment began in January 2006, Ms. Pai, 38, from Shenyang couldn't move her body beneath the injury site, and it was unable to control her bowel movements. Within 8 months with the treatment she regained movement in both her legs, could bend her knees (although the toes of one foot were still paralyzed) and was even able to walk with crutches.<br /><br />Razvan Iordache, a Romanian citizen aged 30, travelled to China for several bouts of stem cell treatment following an accident while diving in to a river that left him paralyzed from your neck down. Following his treatments, Razan reported in 2008 that does not only could he moved to his arms almost normally, and could feel pain in several of his fingers, he could "even feel warm and cold" sensations. He went on to add the following: "Now I will control my urine for 10 mins and the sensation both for urine and stool is way better. Generally, my system is more powerful than ever before."<br /><br />Donald Maricelli, a 54 year old US citizen, a break down spinal cord injury using a fall in 2002. He underwent a surgical procedure to correct his lack of sensation in his lower body, however there was complications and Donald stayed in a worse state than ever before. Before arriving for treatment in China, he was still unable to walk unaided. Following the treatment, which commenced in November 2007, Donald makes significant improvements. He regained sensation throughout most of his abdomen, and the sensation in his legs also improved. Particularly important, the sensation on the bottom of his feet returned, helping him to walk without tripping. Most important to Donald was that he regained control and strength in his left leg, allowing him to walk significant distances and are a symbol of prolonged periods of time.<br /><br />There are many more success stories from patients who've received this pioneering treatment to assist correct varying examples of spinal cord injury. However, it is usually important to remember that not all patients recover the identical functions in the same period of time. A lot of hard work goes into the post treatment rehabilitation, also it takes great drive, determination and ambition to enable the body to get back to more regular functionality. However, the task being done by scientists and clinics in China has shown time and again that stem cells hold an essential key to the future of helping people with spinal cord injuries recover their lost functions. On a monthly basis, more and more people are going to various cities across the country that offer different packages of treatment depending on precisely what injury continues to be inflicted. The level of service has improved greatly in recent years, and continues to improve every month, meaning that those unfortunate enough to possess suffered spinal cord injuries need no more feel theirs can be a lost cause. There exists a very real chance how the standard of living of any patient may be improved with little pain, little hospital time, along with a little motivation. The existing evidence shows that stem cell therapy for spinal-cord injuries is the answer.