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| - | + | Stem Cell Strategy to Spinal Cord Injuries: The newest Frontier<br /><br />[http://www.kneestemcells.com Knee Stem Cell Treatment] - Spinal cord injuries are injuries that happen to any level of the spinal-cord. Although the hard bones with the spinal column protect the soft tissues from the spinal cord, vertebrae can nonetheless be broken or dislocated in a number of ways and cause traumatic problems for the spinal cord. Spinal cord injuries vary inside their severity, but almost inevitably result in various forms of compromised functionality because the spinal cord is in effect the primary pathway for information to visit around the human body. Exactly what body functions are impaired through the injury will depend on the area of the spine which has been damaged and the extent that the spine may be affected. Although serious impacts including falls and motor vehicle accidents account for many spinal-cord injuries, tumors growing near to the column can also damage sensitive nerve tissue and possess the same effects.<br /><br />[http://www.kneestemcells.com Knee Stem Cells] - For many years scientists have been trying to try and find a way to remedy the different ailments that vertebrae injuries can bring, though limited success. However, in recent years a pioneering new technology has emerged that is helping thousands of people around the world regain part, it not exclusively, of their previously lost mobility. That treatment methods are the use of stem cells.<br /><br />What exactly are Stem Cells and Stem Cell Treatments?<br /><br />[http://www.kneestemcells.com Knee Stem Cells] - Stem cells are located in all multi cellular organisms and so are characterized by their ability to tell apart into a diverse array of specialized cells when they divide and renew themselves. They are remarkable for their ability to regenerate themselves into almost any other human cell. Their used in the treatment of various diseases and types of conditions, from Leukemia to Multiple Sclerosis, is now becoming more common. Based on the condition, stem cells may be transplanted into the patient to help renew and regenerate previously damaged cells, giving patients renewed hope when, before, no reliable treatment existed.<br /><br />This principle has become being applied to treating spinal cord injuries using stem cells, and in instances where the patient has not yet experienced a complete spinal cord injury, i.e. a complete severing of the vertebrae leading to a loss of function underneath the 'neurological' level. There has been great success in helping patients recover greater sensory and physiological ability.<br /><br />Vertebrae Injury: How Stem Cell Treatment Works<br /><br />If you have trauma to the spinal cord, myelopathy (damage to the fibres that carry messages to and from the brain) has occurred. These 'myelinated fibre tracts' would be the focus of stem cell treatment, and therefore are the nerve cells the treatment helps to regenerate. The task usually follows three phases in most cases requires no longer when compared to a period of around five weeks in medical treatment for monitoring:<br /><br />Phase one requires the harvesting of stem cells. Cells are extracted from a fetus's umbilical cord. They are then put through an activity whereby they are isolated and purified before they are finally cultured to be suitable for clinical use.<br /><br />Phase two is the transplantation of the stem cells. This is achieved in one of three ways:<br /><br />1) Lumbar puncture - a process used where stem cells could be injected directly into the backbone.<br /><br />2) Intravenous injection- stem cells are injected to the patient's vein.<br /><br />3) Tissue injection - direct injection into target tissues.<br /><br />Phase three requires the monitoring of the patient to make certain there are no adverse negative effects. The only side effects reported thus far were caused by the lumbar puncture, and not the stem cell treatment itself, with only 15% of patients reporting mild headaches. During the time under medical supervision, patients undergo various physiotherapy activities along with other treatments as necessary.<br /><br />Stem Cell Research and Treatment in China<br /><br />China is fast-becoming a world leader in stem cell research, and is also now a major centre for the stem cell treatment of many diseases and types of conditions. The Chinese government has poured many millions of dollars into research on regenerative medicine, understanding that investment has really borne fruit during the last few years. As a result of this expanded investment, Chinese contributions to scientific journals on regenerative medicine topics leapt from 37 in year 2000 to 1,116 in 2008, exceeded only by the contributions of experts in america, Germany, Japan as well as the UK.<br /><br />The government in addition has aggressively recruited high-caliber scientists trained abroad in search of its ambition to turn into a world leader within the field. Indeed, the McLaughlin-Rotman Centre for Global Health commented that, "the government's policy of attracting highly educated Chinese nationals back to China has contributed significantly towards the country's success in the field." The authors were "amazed that most the top Chinese researchers in the regenerative medicine field had been educated in the US and also the UK and gained extensive practical knowledge there in cutting edge research."<br /><br />Although in the past treatment in China may have been considered risky as a result of lax health and safety laws, recent times have seen an increase in legislation protecting the individual, and improving the functionality of clinics. Since 2009, evidence of safety and efficacy through clinical trials is required by China's Secretary of state for Health for all stem cell and gene therapies, making certain Chinese clinics meet international standards within their qualifications and methodology. At the time of January 2010, about 1,500 patients had received botox cosmetic injections for spinal cord injury at one Beijing clinic alone, including roughly 1,000 foreigners.<br /><br />Additionally, China has long held a place at the forefront of stem cell research to treat all manner of conditions. A number of China's notable contributions to stem cell research are: <br /><br />By transferring the nucleus of your human skin cell into the immature ovum cell of the rabbit, researchers from your Shanghai hospital successfully produced embryonic human cells.<br />China thus far has created at least 25 human embryonic stem cell lines (some estimate over 70 stem cell lines), four of which are of a specialized type that at that time only two other groups worldwide had was able to create.<br />Harboured several human tissue types, created artificially, including blood vessel, tendon, bone, cartilage, skin, cornea and muscle fibre.<br />Furthermore, Chinese researchers are involved with a myriad of projects to aid aid patients through regenerative medicine and stem cell therapy. Below are several projects underway within Chinese institutions: <br /><br />ChinaSCINet, a consortium of 27 medical facilities, are beginning phase 2 clinical trials to test the efficacy and safety of employing cord blood stem cells and oral lithium to deal with about 40 patients with vertebrae injuries.<br />Clinical trials are underway on the use of stem cell therapies to take care of patients of cardiac arrest, artery obstruction, and liver and neural diseases.<br />Studies are underway on the potential use of stem cells to deal with heart, liver and blood diseases, eye cataracts, also to combat aging.<br />Testimonials from the Treatment of Spinal-cord Injuries in China<br /><br />Lots of people of all ages and with varying levels of injury have received stem cell treatment in China over the last few years. It is important to keep in mind that not every patient will react as well as others, and that the age of the patient and the severity of the injury greatly affect the likelihood of recovery. However, there have been many success stories from both Chinese citizens and foreigners.<br /><br />Before her treatment began in January 2006, Ms. Pai, 38, from Shenyang couldn't move her body below the injury site, and it was unable to control her going number 2. Within 8 months of the treatment she regained movement in both her legs, could bend her knees (even though the toes of one foot remained paralyzed) and was even capable of walk with crutches.<br /><br />Razvan Iordache, a Romanian citizen aged 30, travelled to China for a number of bouts of stem cell treatment following a major accident while diving into a river that left him paralyzed from the neck down. Following his treatments, Razan reported in 2008 that not only could he moved to his arms almost normally, and could feel pain in several of his fingers, he could "even feel warm and cold" sensations. He proceeded to add the following: "Now I'm able to control my urine for Ten minutes and the sensation for both urine and stool is more preferable. Generally, my system is more powerful than ever before."<br /><br />Donald Maricelli, a 54 year old US citizen, suffered a spinal cord injury using a fall in 2002. He underwent an operation to correct his not enough sensation in his lower body, however there have been complications and Donald was left in a worse state than before. Before arriving for treatment in China, he was still unable to walk unaided. Pursuing the treatment, which commenced in November 2007, Donald has made significant improvements. He regained sensation throughout nearly all of his abdomen, and also the sensation in his legs also improved. Particularly crucial, the sensation on the bottom of his feet went back, helping him simply to walk without tripping. Most critical to Donald was he regained control and strength in the left leg, allowing him simply to walk significant distances and indicate prolonged periods of time.<br /><br />There are many more success stories from patients who have received this pioneering treatment to help correct varying degrees of spinal cord injury. However, it will always be important to remember that not all patients recover exactly the same functions in the same time frame. A lot of hard work switches into the post treatment rehabilitation, also it takes great drive, determination and ambition to enable the body to get back to more regular functionality. However, the work being done by scientists and clinics in China indicates time and again that stem cells hold a very important key to the future of helping individuals with spinal cord injuries recover their lost functions. On a monthly basis, more and more people are going to various cities round the country that offer different packages of treatment according to precisely what injury has been inflicted. The level of service has improved greatly recently, and continues to improve each month, meaning that those unfortunate enough to have suffered spinal cord injuries need no more feel theirs is a lost cause. There is a very real chance how the standard of living of any patient can be improved with little pain, little hospital time, plus a little motivation. The existing evidence shows that stem cell therapy for spinal-cord injuries is the solution. | |
Edição atual tal como 08h26min de 31 de janeiro de 2015
Stem Cell Strategy to Spinal Cord Injuries: The newest Frontier
Knee Stem Cell Treatment - Spinal cord injuries are injuries that happen to any level of the spinal-cord. Although the hard bones with the spinal column protect the soft tissues from the spinal cord, vertebrae can nonetheless be broken or dislocated in a number of ways and cause traumatic problems for the spinal cord. Spinal cord injuries vary inside their severity, but almost inevitably result in various forms of compromised functionality because the spinal cord is in effect the primary pathway for information to visit around the human body. Exactly what body functions are impaired through the injury will depend on the area of the spine which has been damaged and the extent that the spine may be affected. Although serious impacts including falls and motor vehicle accidents account for many spinal-cord injuries, tumors growing near to the column can also damage sensitive nerve tissue and possess the same effects.
Knee Stem Cells - For many years scientists have been trying to try and find a way to remedy the different ailments that vertebrae injuries can bring, though limited success. However, in recent years a pioneering new technology has emerged that is helping thousands of people around the world regain part, it not exclusively, of their previously lost mobility. That treatment methods are the use of stem cells.
What exactly are Stem Cells and Stem Cell Treatments?
Knee Stem Cells - Stem cells are located in all multi cellular organisms and so are characterized by their ability to tell apart into a diverse array of specialized cells when they divide and renew themselves. They are remarkable for their ability to regenerate themselves into almost any other human cell. Their used in the treatment of various diseases and types of conditions, from Leukemia to Multiple Sclerosis, is now becoming more common. Based on the condition, stem cells may be transplanted into the patient to help renew and regenerate previously damaged cells, giving patients renewed hope when, before, no reliable treatment existed.
This principle has become being applied to treating spinal cord injuries using stem cells, and in instances where the patient has not yet experienced a complete spinal cord injury, i.e. a complete severing of the vertebrae leading to a loss of function underneath the 'neurological' level. There has been great success in helping patients recover greater sensory and physiological ability.
Vertebrae Injury: How Stem Cell Treatment Works
If you have trauma to the spinal cord, myelopathy (damage to the fibres that carry messages to and from the brain) has occurred. These 'myelinated fibre tracts' would be the focus of stem cell treatment, and therefore are the nerve cells the treatment helps to regenerate. The task usually follows three phases in most cases requires no longer when compared to a period of around five weeks in medical treatment for monitoring:
Phase one requires the harvesting of stem cells. Cells are extracted from a fetus's umbilical cord. They are then put through an activity whereby they are isolated and purified before they are finally cultured to be suitable for clinical use.
Phase two is the transplantation of the stem cells. This is achieved in one of three ways:
1) Lumbar puncture - a process used where stem cells could be injected directly into the backbone.
2) Intravenous injection- stem cells are injected to the patient's vein.
3) Tissue injection - direct injection into target tissues.
Phase three requires the monitoring of the patient to make certain there are no adverse negative effects. The only side effects reported thus far were caused by the lumbar puncture, and not the stem cell treatment itself, with only 15% of patients reporting mild headaches. During the time under medical supervision, patients undergo various physiotherapy activities along with other treatments as necessary.
Stem Cell Research and Treatment in China
China is fast-becoming a world leader in stem cell research, and is also now a major centre for the stem cell treatment of many diseases and types of conditions. The Chinese government has poured many millions of dollars into research on regenerative medicine, understanding that investment has really borne fruit during the last few years. As a result of this expanded investment, Chinese contributions to scientific journals on regenerative medicine topics leapt from 37 in year 2000 to 1,116 in 2008, exceeded only by the contributions of experts in america, Germany, Japan as well as the UK.
The government in addition has aggressively recruited high-caliber scientists trained abroad in search of its ambition to turn into a world leader within the field. Indeed, the McLaughlin-Rotman Centre for Global Health commented that, "the government's policy of attracting highly educated Chinese nationals back to China has contributed significantly towards the country's success in the field." The authors were "amazed that most the top Chinese researchers in the regenerative medicine field had been educated in the US and also the UK and gained extensive practical knowledge there in cutting edge research."
Although in the past treatment in China may have been considered risky as a result of lax health and safety laws, recent times have seen an increase in legislation protecting the individual, and improving the functionality of clinics. Since 2009, evidence of safety and efficacy through clinical trials is required by China's Secretary of state for Health for all stem cell and gene therapies, making certain Chinese clinics meet international standards within their qualifications and methodology. At the time of January 2010, about 1,500 patients had received botox cosmetic injections for spinal cord injury at one Beijing clinic alone, including roughly 1,000 foreigners.
Additionally, China has long held a place at the forefront of stem cell research to treat all manner of conditions. A number of China's notable contributions to stem cell research are:
By transferring the nucleus of your human skin cell into the immature ovum cell of the rabbit, researchers from your Shanghai hospital successfully produced embryonic human cells.
China thus far has created at least 25 human embryonic stem cell lines (some estimate over 70 stem cell lines), four of which are of a specialized type that at that time only two other groups worldwide had was able to create.
Harboured several human tissue types, created artificially, including blood vessel, tendon, bone, cartilage, skin, cornea and muscle fibre.
Furthermore, Chinese researchers are involved with a myriad of projects to aid aid patients through regenerative medicine and stem cell therapy. Below are several projects underway within Chinese institutions:
ChinaSCINet, a consortium of 27 medical facilities, are beginning phase 2 clinical trials to test the efficacy and safety of employing cord blood stem cells and oral lithium to deal with about 40 patients with vertebrae injuries.
Clinical trials are underway on the use of stem cell therapies to take care of patients of cardiac arrest, artery obstruction, and liver and neural diseases.
Studies are underway on the potential use of stem cells to deal with heart, liver and blood diseases, eye cataracts, also to combat aging.
Testimonials from the Treatment of Spinal-cord Injuries in China
Lots of people of all ages and with varying levels of injury have received stem cell treatment in China over the last few years. It is important to keep in mind that not every patient will react as well as others, and that the age of the patient and the severity of the injury greatly affect the likelihood of recovery. However, there have been many success stories from both Chinese citizens and foreigners.
Before her treatment began in January 2006, Ms. Pai, 38, from Shenyang couldn't move her body below the injury site, and it was unable to control her going number 2. Within 8 months of the treatment she regained movement in both her legs, could bend her knees (even though the toes of one foot remained paralyzed) and was even capable of walk with crutches.
Razvan Iordache, a Romanian citizen aged 30, travelled to China for a number of bouts of stem cell treatment following a major accident while diving into a river that left him paralyzed from the neck down. Following his treatments, Razan reported in 2008 that not only could he moved to his arms almost normally, and could feel pain in several of his fingers, he could "even feel warm and cold" sensations. He proceeded to add the following: "Now I'm able to control my urine for Ten minutes and the sensation for both urine and stool is more preferable. Generally, my system is more powerful than ever before."
Donald Maricelli, a 54 year old US citizen, suffered a spinal cord injury using a fall in 2002. He underwent an operation to correct his not enough sensation in his lower body, however there have been complications and Donald was left in a worse state than before. Before arriving for treatment in China, he was still unable to walk unaided. Pursuing the treatment, which commenced in November 2007, Donald has made significant improvements. He regained sensation throughout nearly all of his abdomen, and also the sensation in his legs also improved. Particularly crucial, the sensation on the bottom of his feet went back, helping him simply to walk without tripping. Most critical to Donald was he regained control and strength in the left leg, allowing him simply to walk significant distances and indicate prolonged periods of time.
There are many more success stories from patients who have received this pioneering treatment to help correct varying degrees of spinal cord injury. However, it will always be important to remember that not all patients recover exactly the same functions in the same time frame. A lot of hard work switches into the post treatment rehabilitation, also it takes great drive, determination and ambition to enable the body to get back to more regular functionality. However, the work being done by scientists and clinics in China indicates time and again that stem cells hold a very important key to the future of helping individuals with spinal cord injuries recover their lost functions. On a monthly basis, more and more people are going to various cities round the country that offer different packages of treatment according to precisely what injury has been inflicted. The level of service has improved greatly recently, and continues to improve each month, meaning that those unfortunate enough to have suffered spinal cord injuries need no more feel theirs is a lost cause. There is a very real chance how the standard of living of any patient can be improved with little pain, little hospital time, plus a little motivation. The existing evidence shows that stem cell therapy for spinal-cord injuries is the solution.
