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Can You Give Kids Vitamin C Supplements?
The position of vitamin C in cancer prevention is unclear. Research indicate that vitamin C reduces oxidative stress (18) Excessive plasma degree of vitamin C is related to decrease gastrointestinal most cancers incidence in all probability resulting from its protecting effects towards dietary carcinogenic nitroso compounds (19) Intake of nutritional vitamins A, C, or E decreased vitamin c for colds danger of cervical most cancers (20) , but they don't prevent gastrointestinal (21) , prostate (22) , lung cancers (23) and other cancer incidence or have an effect on most cancers mortality (24) Further, vitamin C supplementation is associated with elevated risk of liver cancer, although this impact is not noticed with vitamin C from dietary sources (25)
Vitamin C is water soluble, with dietary excesses not absorbed, and excesses within the blood quickly excreted within the urine. It displays remarkably low toxicity. The LD 50 (the dose that can kill 50% of a population) in rats is mostly accepted to be 11.9�grams per kilogram of physique weight when given by compelled gavage (orally). The mechanism of dying from such doses (1.2% of body weight, or 0.84�kg for a 70�kg human) is unknown, however could also be more mechanical than chemical. 102 The LD 50 in people stays unknown, given lack of any unintentional or intentional poisoning dying information. Dietary sources edit.
Taking vitamin C, beta-carotene, selenium, and vitamin E collectively might decrease the effectiveness of some drugs used for decreasing cholesterol. It is not known if vitamin C alone decreases the effectiveness of some drugs used for reducing cholesterol. Taking vitamin C together with vitamin E, beta-carotene, and selenium may decrease some of the useful effects of niacin. Niacin can improve the nice cholesterol. Taking vitamin C along with these other nutritional vitamins would possibly decrease the effectiveness of niacin for growing good ldl cholesterol. Vitamin C might decrease how shortly the physique eliminates choline magnesium trisalicylate (Trilisate). But it's not clear if this interplay is an enormous concern.
There is some proof, though controversial, that vitamin C interacts with anticoagulant medications (blood thinners) like warfarin (Coumadin). Large doses of vitamin C could block the motion of warfarin, requiring an increase in dose to keep up its effectiveness. People on anticoagulants ought to restrict their vitamin C intake to 1 gram/day and have their prothrombin time monitored by the clinician following their anticoagulant remedy http://www.agelessway.org/lifec.html. As a result of excessive doses of vitamin C have additionally been found to intrude with the interpretation of certain laboratory exams (e.g., serum bilirubin, serum creatinine, and the guaiac assay for occult blood), it is very important inform one's health care supplier of any recent complement use (144)
Lowering high blood pressure Taking vitamin C together with conventional hypertension medications appears to lower systolic blood pressure (the highest quantity in a blood pressure reading) by a small quantity, however does not appear to decrease diastolic strain (the underside quantity). Taking vitamin C dietary supplements alone, although, doesn�t seem to have an effect on blood pressure. Slowing the worsening of osteoarthritis Obtaining vitamin C from dietary sources seems to prevent cartilage loss and worsening of symptoms in individuals with osteoarthritis. Decreasing protein within the urine of people with kind 2 diabetes (albuminuria) This would possibly help to lower the risk of developing severe kidney illness.
These pilot and phase I examine outcomes encourage larger, longer-period phase II medical trials that check the efficacy of intravenous ascorbic acid in illness progression and general survival. Such part II clinical trials are currently under manner (117) Because totally different cancer subtypes may be recalcitrant or require different doses of intravenous vitamin C, section II trials are essential before use of intravenous vitamin C as an anti-tumor agent may be absolutely realized (118) For information about the usage of high-dose intravenous vitamin C as an adjunct in cancer remedy, go to the University of Kansas Medical Heart Program in Integrative Medicine web site
Treating ulcers within the stomach attributable to micro organism called H. pylori Taking vitamin C seems to decrease a few of the unwanted effects brought on by therapy. After H. pylori micro organism are killed, vitamin C appears to decrease the incidence of precancerous adjustments in abdomen tissue. Decreasing ldl cholesterol Taking vitamin C daily doesn�t seem to lower cholesterol in individuals whose cholesterol just isn't too excessive to start out with. The impact of vitamin C on cholesterol levels in patients with high ldl cholesterol isn't recognized. Cancer (Esophageal most cancers, and colorectal most cancers) Taking vitamin C together with beta-carotene plus vitamin E doesn't seem to prevent these types of cancer.
Cataracts There's conflicting details about the use of vitamin C to forestall cataracts. Vitamin C plus vitamin E and beta-carotene does not appear to have any vital impact on age-associated lack of imaginative and prescient due to cataracts in properly-nourished people who take the supplement lengthy-time period (for a median of 6.three years). Then again Additional Info, other analysis means that taking multivitamins that contain vitamin C for 10 years appears to stop cataracts. Use of dietary supplements for shorter periods would not seem to work. Vitamin C is required for the right growth and function of many components of the body. It also plays an important position in maintaining proper immune operate.
