Astaxanthin And Cancer
De BISAWiki
Astaxanthin otherwise known as ASTA, is often a purple crystalline powder, insoluble in water, soluble in a solvent like dimethyl sulfoxide, acetone, chloroform. The Astaxanthin is extremely unstable when encountered with light, heat easily biodegradable. In 1938 scientists the 1st time isolated this natural antioxidant named astaxanthin from lobster. Inside the ensuing decades, the scientists figure out the dwelling and biological activity of the antioxidant.Astaxanthin is a red carotenoid, the highest-level product for that synthesis of carotenoids, -carotene, lutein, canthaxanthin, lycopene are carotenoids synthesis intermediates. Therefore, naturally, astaxanthin has the strongest antioxidant activity. Based on cosmetic raw material suppliers, what's more, it has the role of anti-aging, anti-tumor, preventing cardiovascular diseases.Astaxanthin can be a chain breaking antioxidants, has strong antioxidant effect. The scientists in contrast to carotenoids which the structure is the identical, nevertheless the conjugated double bond number is different, like lutein, zeaxanthin, lycopene, different zeaxanthin. Carotene and its particular derivatives in oxidation, the quenching ability of active oxygen increased with all the conjugated double bond, whereinastaxanthin while using strongest antioxidant capacity. Use containing ferrous ion of heme protein like a free radical generator, linoleic acid for the receiver, detection of various carotenoids and tocopherols and its particular derivatives ( VE ) free radical scavenging dose ratio. Researches found that the capability of astaxanthin scavenging toxin could be the strongest, consider carotene and it is derivatives in hydroxy and keto existence as well as the numbers is vital for your toxin scavenging effect.The biologists experimental results reveal that, cancer is closely associated with human genetics and somatic abnormal splitting. In the process of human metabolism, because obtain the influence of external environment, particulate cell chromosome mutation and mitotic abnormalities, make certain tissue pathologic hyperplasia, to ensure that normal cells develop into cancer cells.Gene is often a subject record various human information, often known as DNA, is double helical chain structure, its mechanism is extremely stable. In the strong external force, this extremely stable structure will collapse, fracture. When gene chain collapse, fracture, intracellular free nucleic acids will on gene chain repair and reconstruction, in this process, the first gene chain information could possibly have lost, increase or completely rewritten. Then, these cells can be turned into a weird, from where they split on the cell, may be the arch-criminal of numerous diseases, cancer is amongst the typical.Information sustained byastaxanthin suppliers, astaxanthin features a strong anti-cancer effect. Effect of astaxanthin on liver cancer show that,astaxanthin in vivo toxicity mechanism induced DNA single strand breaks has reduced effect, reduce aflatoxin B1 and DNA liver and plasma albumin combine, and promoting the in vitro metabolism for another toxic weak aflatoxin M1.Dietary supplementation of astaxanthin can inhibit breast tumor growth, which greatly cuts down on the incidence of breast carcinoma, this function is stronger than - carotene and canthaxanthin. Enlargement from the men's prostate is mainly a result of 5-a- reductase, astaxanthin can effectively inhibit the enzyme activity, therefore complement astaxanthin is recognized as the effective way to prevent prostate hyperplasia and prostate type of cancer.Astaxanthin, can regulate gene expression and induces intercellular information transfer process. Cell gap regulate the communication that cell growth information needed, more valuable is it can inhibit cancer cell proliferation.
